Bariatric Surgery to Correct Morbid Obesity Also Ameliorates Atherosclerosis in Patients with Type 2 Diabetes Mellitus.
نویسندگان
چکیده
Morbid obesity, a physiological dysfunction in humans associated with environmental, genetic and endocrinological origins, has significantly increased in the past few decades in the USA. Many methods have emerged for treating morbid obesity, such as diets, exercise, behavior modification, liposuction, drugs, and surgery; among these, bariatric surgery reduces weight and appears to have other curative effects. Roux-en-Y gastric bypass is the principal form of bariatric surgery, followed by laparoscopic adjustable gastric banding, gastric sleeve operation, duodenojejunal bypass and biliopancreatic diversion. This weight-loss surgery may also affect comorbidities of morbid obesity, such as type 2 diabetes mellitus (T2D), atherosclerosis, hypertension and steatohepatitis. Weight-loss surgery, for example, is associated with a more than 80% diabetes (data indicates > 80%) remission rate in severely obese persons. Empirical evidence also suggests that the use of bariatric surgery reduces atherosclerosis, and may ameliorate other comorbities. This warrants closer examination.
منابع مشابه
White blood cells in obesity and diabetes: effects of weight loss and normalization of glucose metabolism.
White blood cell (WBC) count is elevated in obesity (1) and is a risk factor for atherosclerosis (2). An elevated WBC count is present in impaired glucose tolerance (IGT) (3), and WBC count is associated with macroand microangiopathic complications in type 2 diabetes (4). In both of these studies, the effect was more marked in obese patients. In morbid obesity, bariatric surgery in many cases (...
متن کاملBariatric surgery in type 1 diabetes mellitus; long-term experience in two cases.
In patients with obesity and type 2 diabetes, recommendations for bariatric surgery are well established. However, no consensus exists regarding its role for the management of patients with type 1 diabetes and morbid obesity. We present the long-term follow-up of two women with type 1 diabetes, morbid obesity and associated comorbidities, who underwent malabsorptive bariatric surgery. More than...
متن کاملThe growing role of bariatric surgery in the management of type 2 diabetes: evidences and open questions.
The use of bariatric surgery in the clinical management of type 2 diabetes has been recently endorsed in the clinical practice recommendations released by the most influential diabetologic associations. However, authoritative critic voices about the application of metabolic surgery in type 2 diabetes continue to appear in diabetologic literature. In this review, we will try therefore to underst...
متن کاملInvestigating Changes in the Serum Iron, TIBC (Total Iron Binding Capacity) and Transferrin Levels in Patients with Morbid Obesity Undergoing Bariatric Surgery in Kerman in 2018: A Short Report
Background and Objectives: Bariatric surgery is one of the most effective treatments for obesity. This study was designed to investigate changes in the serum iron, TIBC (Total Iron Binding Capacity) and transferrin levels in patients with morbid obesity undergoing bariatric surgery in Kerman in 2018. Materials and Methods: This prospective study was carried out on 65 participants who had gone ...
متن کاملTreatment of diabetes prior to and after bariatric surgery.
The number of patients undergoing bariatric surgery for morbid obesity is increasing. Type 2 diabetes is common among patients undergoing bariatric surgery. The effect of bariatric surgery on glycemia is profound in patients with diabetes and might vary between different bariatric surgical procedures. Therefore, almost invariably, there is a need to adjust antidiabetic drug dosages in the posto...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- American journal of biomedical sciences
دوره 1 1 شماره
صفحات -
تاریخ انتشار 2009